Serine
[대역어] None
[용어속성] Compound
[용어속성] Compound
Synthesis and structure-activity relationship study of saponin-based membrane fusion inhibitors against SARS-CoV-2
SARS-CoV-2에 대한 사포닌계 막융합 억제제의 합성 및 구조-활성 관계 연구
Article
[키워드] antiviral agent
Antiviral agents
antiviral efficacy
Cell
cell entry
Cell fusion
Complex molecule
Complex molecules synthesis
component
Compound
coronavirus
coronavirus variants
COVID-19
Critical
derivative
develop
Effectiveness
endosomal
experiment
fusion
Glucose
host cell
host cell membranes
inhibit
inhibited
inhibitor
inhibitors
membrane fusion
protease
Saponin
saponins
Saponins.
SARS-CoV-2
SARS-CoV-2 entry
SARS-CoV-2 variant
SARS-CoV-2 variants
Serine
sugar
synthesis
the SARS-CoV-2
transmembrane
[DOI] 10.1016/j.bioorg.2022.105985 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.bioorg.2022.105985 PMC 바로가기 [Article Type] Article
Molecular mechanisms involved in anosmia induced by SARS-CoV-2, with a focus on the transmembrane serine protease TMPRSS2
막횡단 세린 프로테아제 TMPRSS2를 중심으로 SARS-CoV-2에 의해 유도된 후각장애와 관련된 분자 기전
Review
[키워드] Anosmia
Apoptosis
blockade
camostat
caused
cell entry
cellular and molecular
chromosome
chromosome 21
cleaving
Delta
dependent on
disease
disorder
dysfunction
entry of SARS-CoV-2
event
ExoN
exons
facilitate
functional
gene encoding
Genetic variations
help
host cell
Inflammation
involved
mechanism
nafamostat
neuronal
number of symptoms
olfactory dysfunction
olfactory neuroepithelium
omicron
overcome
pandemic virus
receptor
receptors
risk
SARS-CoV-2
Serine
serine protease
serine protease inhibitor
serine protease inhibitors
shown
strain
Strains
Symptoms
therapeutic
TMPRSS2
transmembrane serine protease
viral S protein
virus
[DOI] 10.1007/s00705-022-05545-0 PMC 바로가기 [Article Type] Review
[DOI] 10.1007/s00705-022-05545-0 PMC 바로가기 [Article Type] Review
Human genetic basis of severe or critical illness in COVID-19
Article
[키워드] acute respiratory syndrome
affecting
association
Asymptomatic
base
caused
contribute
coronavirus
COVID-19
Critical
Critical illness
death
determinant
disease
disease severity
enhanced
Enzymes
Factor
Genetic
Genetic variation
genetic.
Host
Human
human leukocyte antigen
immune component
indicated
Interaction
Interleukins
loci
mild infection
morbidity and mortality
multi-organ dysfunction
outcome
Precision
preventive measure
Respiratory failure
SARS-CoV-2
SARS-CoV-2 receptor
Serine
severity of COVID-19
Toll-like receptor
transmembrane
[DOI] 10.3389/fcimb.2022.963239 PMC 바로가기
[DOI] 10.3389/fcimb.2022.963239 PMC 바로가기
Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19
Article
[키워드] ACE2 receptor
anti-SARS-CoV-2
antibody
cellular protease
COVID-19
COVID-19 disease
disease
dominant
exonuclease
Genetic
genetic susceptibility
Genotype
Haplotype
high risk
individual
Infection
lactic acid dehydrogenase
LDH
Patient
patients with COVID-19
polymorphism
Polymorphisms
Protective
risk
risk of COVID-19
RT-PCR test
SARS-CoV-2
SARS-COV-2 infection
Serine
TaqMan assays
target cells
the SARS-CoV-2
TMPRSS2
transmembrane
transmembrane serine protease-2 (TMPRSS2).
with COVID-19
[DOI] 10.3390/v14091976 PMC 바로가기
[DOI] 10.3390/v14091976 PMC 바로가기
SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19
Article
[키워드] ACE2
ACE2 protein
cells
contribute
correlated
COVID-19
COVID-19 cohort
Degradation
E3 ligase
ENhance
entry receptor
epithelial
epithelial cell
epithelial cells
Exosome
Exosomes
humanized
Infection
Live virus
lysine
MAP4K3/GLK
mice
overexpression
pathogenesis of COVID-19
patients
phosphorylated
prevented
pseudovirus infection
residue
RNA-sequencing
SARS-CoV-2
SARS-CoV-2 pseudovirus
SARS-CoV-2 spike
SARS-CoV-2 spike protein
secretion
Serine
serum exosome
severity
stability
the SARS-CoV-2
transported
UBR4
UBR4.
Vesicle
with COVID-19
[DOI] 10.15252/emmm.202215904 PMC 바로가기 [Article Type] Article
[DOI] 10.15252/emmm.202215904 PMC 바로가기 [Article Type] Article
Repurposing vilanterol as a novel potential antifungal for Candida albicans: In-silico & in-vitro approach
Research article
[키워드] Acridine orange and Ethidium bromide
Alter
Amino acids CYSCystine
Analysis
AO/EBAcridine orange and Ethidium bromide
approach
binding
binding free energy
C. albican
C. albicans
Candida
Candida albican
carried
cause
cell membrane
chronic Conditions obstructive pulmonary disease
Clinical and Laboratory Standards Institute
clinical study
CLSIClinical and Laboratory Standards Institute
complex
Computational drug
Concentration
COPDchronic Conditions obstructive pulmonary disease
Cystine
demethylase
diffusion
Dimethyl sulfoxide
disrupt
DMSODimethyl sulfoxide
docking method
dose
drug
drug interaction
Drug screening
drugs
Erg11pLanosterol 14-alpha demethylase
FDAThe United States Food and Drug Administration
fluorescent
fungicidal
fungicidal activity
glycine
GLYGlycine
Health
High-throughput virtual screening
HISHistidine
histidine
HTVSHigh-throughput virtual screening
humans
In-vitro
infect
infections
inhibitory concentration
initial
Interaction
lanosterol
Lanosterol 14-alpha demethylase
MDSMolecular Dynamics Simulations
MICMinimum inhibitory concentration
Microscopy
Minimum inhibitory concentration
MMGBSAMolecular mechanics energies with generalized born surface area
Molecular dynamics simulation
molecular dynamics simulations
Molecular mechanics energies with generalized born surface area
mortality rate
PBSPhosphate buffer saline
PDBProtein Data Bank
Phenylalanine
PHEPhenylalanine
Phosphate buffer saline
Phosphatidylcholines
Picoseconds
POPCPhosphatidylcholines
Protein Data Bank
psPicoseconds
repurposing
Safe
SDStandard deviation
Serine
SERSerine
SPStandard-precision
Standard deviation
Standard-precision
tested
The United States Food and Drug Administration
tyrosine
TYRTyrosine
Variable-dielectric surface generalized born model 2.0
VSGB 2.0Variable-dielectric surface generalized born model 2.0
XPXtra-precision
Xtra-precision
Yeast extract/peptone/dextrose
YPDYeast extract/peptone/dextrose
[DOI] 10.1016/j.medidd.2022.100137 [Article Type] Research article
[DOI] 10.1016/j.medidd.2022.100137 [Article Type] Research article
COVID-19 Infections in Gonads: Consequences on Fertility?
생식선의 COVID-19 감염: 불임에 대한 결과?
Review
Published on
Journal: Hormone and metabolic research = Hormon- und Stoff
[Category] COVID19(2023년), MERS, SARS, 진단,
Journal: Hormone and metabolic research = Hormon- und Stoff
[Category] COVID19(2023년), MERS, SARS, 진단,
[키워드] ACE2
addition
Affect
angiotensin-converting enzyme 2
cell type
changes in
consequence
COVID
COVID-19
COVID-19 infection
COVID-19 pandemic
decrease
described
dysfunction
Effect
entry pathway
example
expression
healthy
impairing
include
Interaction
knowledge
men
menstrual
mental health issue
Oocyte
ovarian
Premature
protease
Psychological
reduced
reported
SARS-CoV-2
SARS-CoV-2 vaccine
Serine
Sexuality
Stress
tissue
TMPRSS2
transmembrane
women
[DOI] 10.1055/a-1891-6621 PMC 바로가기 [Article Type] Review
[DOI] 10.1055/a-1891-6621 PMC 바로가기 [Article Type] Review
Coronavirus disease 2019 and the placenta: A literature review
코로나바이러스 질병 2019 및 태반: 문헌 검토
Review
[키워드] ACE2
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
angiotensin
Angiotensin-converting enzyme
angiotensin-converting enzyme-2
Antigen
Basigin
canonical
cathepsin B
Cathepsin B/L
caused
CD147
CD26
Chain Reaction
Clinical pathology
coding
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
CTL
dipeptidyl peptidase
Dipeptidyl peptidase-4
DPP4
electron microscopy
eligible
enzyme
evaluate
Express
expressed
Factor
fetal
furin
IFITM1
immunohistochemistry
implicated
In situ hybridization
interferon
involved
literature review
Localization
LY6E
lymphocyte
mechanism
Microscopy
multiple organ
multiple organs
nonspecific
organ systems
Particle
Particles
Pathogenesis
pathogenesis of SARS-CoV-2
pathology
permissiveness
Placenta
placental
Placental infection
placental pathology
polymerase chain
polymerase chain reaction
Pregnancy
pregnancy trimesters
profile
Proteases
Protein
Proteins
receptor
reduce
RNA
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 receptors
Serine
severe acute respiratory syndrome Coronavirus
single-cell analysis
single-cell analysis.
the disease
TMPRSS2
transmembrane
transmembrane protein
transmembrane serine protease
Vascular
viral pathogenesis
Viral RNA
virus
[DOI] 10.1016/j.placenta.2022.07.007 PMC 바로가기 [Article Type] Review
[DOI] 10.1016/j.placenta.2022.07.007 PMC 바로가기 [Article Type] Review
Structural determination of an antibody that specifically recognizes polyethylene glycol with a terminal methoxy group
Research
[키워드] analysis
antibodies
antibody
antigenicity
bind
binding
circulation
complex
cross-reactivity
glycol
humanized
hydrogen bond interaction
hydrogen bond interactions
hydrophobic
hydroxyl groups
IMPROVE
induce
mechanism
Neutral
offer
polar
Polymer
recognize
replacement
residue
resulting
Serine
specificity
therapeutic effects
therapeutic efficacy
Therapeutic molecule
Van
[DOI] 10.1038/s42004-022-00709-0 [Article Type] Research
[DOI] 10.1038/s42004-022-00709-0 [Article Type] Research